Abstract
Timely identification and detection of Myocardial Infarction (MI) are essential for mitigating cardiac tissue injury and reducing mortality risk. For accurate MI prediction, many algorithms based on Deep Learning (DL) have been created. Amongst, The Encoder-Decoder Convolutional Neural Network (E-D CNN) for image segmentation and a separate CNN model for MI prediction were used in the development of the deep network model for MI detection (MIDepnet). However, the E-D CNN involves many parameters and heavy architectures, hindering real-time image segmentation and detection. To address this, Lightweight E-D CNN (L-E-D CNN) segmentation model is developed for effective MI prediction. In this model, split blocks are introduced in L-E-D CNN which constitutes to two channels. The first channel consists of two parallel paths, one with standard convolution and the other with Multi Dense Dilated Depthwise Separable Convolution (MDDDSC) to capture both local and global features. The use of MDDDSC increase the receptive field with less parameters size. The second channel uses two factorized convolutions with an adaptable dilation rate to increase the receptive field without increasing parameters size. Additionally, a segmented mask training, morphological operations and post-processing pipeline are performed to improve segmentation. The segmented mask training is adopted to learn the inner region with and without papillary muscles and the outer ventricular region to enhance the boundary delineation. The predicted inner mask is subtracted from the outer mask to obtain a refined and separated ventricular region. Morphological operations are then applied to smooth boundaries, fill small gaps and remove minor artifacts. Then, the post-processing stage are applied to improve the boundary clarity, reduces noise and enhances segmentation accuracy. Lastly, the CNN-LSTM model is used for MI prediction using the features obtained from the L-E-D CNN. The complete model is termed as Lightweight MIDepnet (LMIDepnet). Finally, the outcomes show that the LMIDepnet algorithm on the Hamad Medical Corporation, Tampere University and Qatar University (HMC-QU) dataset and Realistic Synthetic 2D Ultrasound dataset obtains the accuracy of 95.97% and 94.89%, respectively, compared to the UNet + Support Vector Machine (SVM), UNet + CNN, DeepLabV3 + ResNet50, UNet + DenseNet121, SegNet + Saimese Neural Network (SNN) models.
Keywords
Myocardial Infarction, Deep Learning (Dl), Image Segmentation, Parameter Reduction, Post Training,Downloads
References
- D. Yan, S. Zhan, C. Guo, J. Han, L. Zhan, Q. Zhou, X. Wang, The Role of Myocardial Regeneration, Cardiomyocyte Apoptosis in Acute Myocardial Infarction: A Review of Current Research Trends and Challenges. Journal of Cardiology, 85(4), (2024) 283-292. https://doi.org/10.1016/j.jjcc.2024.09.012
- M.A. Matter, F. Paneni, P. Libby, S. Frantz, B.E. Stähli, C. Templin, A. Mengozzi, Y.J. Wang, T.M. Kündig, L. Räber, F. Ruschitzka, C.M. Matter, Inflammation in Acute Myocardial Infarction: the Good, the Bad and the Ugly. European Heart Journal, 45(2), (2024) 89–103. https://doi.org/10.1093/eurheartj/ehad486
- M. Milosevic, Q. Jin, A. Singh, S. Amal, Applications of AI in Multi-Modal Imaging for Cardiovascular Disease. Frontiers in Radiology, 3, (2024) 1294068. https://doi.org/10.3389/fradi.2023.1294068
- E.G. Akramova, E.V. Vlasova, A.A. Saveliev, E.B. Zakirova, Information Value of Echocardiography in Inferior Myocardial Infarction at Different Stages of Observation. Journal of Clinical Practice, 15(1), (2024) 17–25. https://clinpractice.ru/clinpractice/article/view/580663
- C. Mitchell, P.S. Rahko, L.A. Blauwet, B. Canaday, J.A. Finstuen, M.C. Foster, K. Horton, K.O. Ogunyankin, R.A. Palma, E.J. Velazquez, Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography. Journal of the American Society of Echocardiography, 32(1), (2019) 1–64. https://doi.org/10.1016/j.echo.2018.06.004
- D. Ouyang, B. He, A. Ghorbani, N. Yuan, J. Ebinger, C.P. Langlotz, P.A. Heidenreich, R.A. Harrington, D.H. Liang, E.A. Ashley, J.Y. Zou, Video-Based AI for Beat-to-Beat Assessment of Cardiac Function. Nature, 580(7802), (2020) 252–256. https://doi.org/10.1038/s41586-020-2145-8
- A. Madani, R. Arnaout, M. Mofrad, R. Arnaout, Fast and Accurate View Classification of Echocardiograms using Deep Learning. NPJ Digital Medicine, 1, (2018) 6. https://doi.org/10.1038/s41746-017-0013-1
- J. Zhang, S. Gajjala, P. Agrawal, G.H. Tison, L.A. Hallock, L. Beussink-Nelson, M.H. Lassen, E. Fan, M.A. Aras, C. Jordan, K.E. Fleischmann, M. Melisko, A. Qasim, S.J. Shah, R. Bajcsy, R.C. Deo, Fully Automated Echocardiogram Interpretation in Clinical Practice: Feasibility and Diagnostic Accuracy. Circulation, 138(16), (2018) 1623–1635. https://doi.org/10.1161/CIRCULATIONAHA.118.034338
- A. Degerli, M. Zabihi, S. Kiranyaz, T. Hamid, R. Mazhar, R. Hamila, M. Gabbouj, Early Detection of Myocardial Infarction in Low-Quality Echocardiography. IEEE Access, 9, (2021) 34442–34453. https://doi.org/10.1109/ACCESS.2021.3059595
- C. Tiago, S.R. Snare, J. Šprem, K. McLeod, A Domain Translation Framework with an Adversarial Denoising Diffusion Model to Generate Synthetic Datasets of Echocardiography Images. IEEE Access, IEEE, 11, (2023) 17594–17602. https://doi.org/10.1109/ACCESS.2023.3246762
- B.A. Valanrani, S.D. Suganya, Improving Myocardial Infarction Detection from Echo Images using Contrastive Guided Adversarial Denoising Diffusion Probabilistic Model. International Journal of Engineering Trends and Technology, 72(12), (2024) 285–297. https://doi.org/10.14445/22315381/IJETT-V72I12P124
- Y. Deng, P. Cai, L. Zhang, X. Cao, Y. Chen, S. Jiang, Z. Zhuang, B. Wang, Myocardial Strain Analysis of Echocardiography Based on Deep Learning. Frontiers in Cardiovascular Medicine, 9, (2022) 1067760. https://doi.org/10.3389/fcvm.2022.1067760
- X. Lin, F. Yang, Y. Chen, X. Chen, W. Wang, X. Chen, Q. Wang, L. Zhang, H. Guo, B. Liu, L. Yu, K. He, Echocardiography-Based AI Detection of Regional Wall Motion Abnormalities and Quantification of Cardiac Function in Myocardial Infarction. Frontiers in Cardiovascular Medicine, 9, (2022) 903660. https://doi.org/10.3389/fcvm.2022.903660
- O. Hamila, S. Ramanna, C.J. Henry, S. Kiranyaz, R. Hamila, R. Mazhar, T. Hamid, Fully Automated 2D and 3D Convolutional Neural Networks Pipeline for Video Segmentation and Myocardial Infarction Detection in Echocardiography. Multimedia Tools and Applications, 81(26), (2022) 37417–37439. https://doi.org/10.1007/s11042-021-11579-4
- G. Zamzmi, S. Rajaraman, L.Y. Hsu, V. Sachdev, S. Antani, Real-Time Echocardiography Image Analysis and Quantification of Cardiac Indices. Medical Image Analysis, 80, (2022) 102438. https://doi.org/10.1016/j.media.2022.102438
- E. Evain, Y. Sun, K. Faraz, D. Garcia, E. Saloux, B.L. Gerber, M. Craene, O. Bernard, Motion Estimation by Deep Learning in 2D Echocardiography: Synthetic Dataset and Validation. IEEE Transactions on Medical Imaging, IEEE, 41(8), (2022) 1911–1924. https://doi.org/10.1109/TMI.2022.3151606
- C. Balakrishnan, V.D. Ambeth Kumar, IoT-Enabled Classification of Echocardiogram Images for Cardiovascular Disease Risk Prediction with Pre-Trained Recurrent Convolutional Neural Networks. Diagnostics, 13(4), (2023) 775. https://doi.org/10.3390/diagnostics13040775
- T. Nguyen, P. Nguyen, D. Tran, H. Pham, Q. Nguyen, T. Le, H. Van, B. Do, P. Tran, V. Le, T. Nguyen, H. Pham, Ensemble Learning of Myocardial Displacements for Myocardial Infarction Detection in Echocardiography. Frontiers in Cardiovascular Medicine, 10, (2023) 1185172. https://doi.org/10.3389/fcvm.2023.1185172
- S. Deepika, N. Jaisankar, Detecting and classifying myocardial infarction in Echocardiogram Frames with an Enhanced CNN Algorithm and ECV-3D Network. IEEE Access, IEEE, 12, (2024) 51690-51703. https://doi.org/10.1109/ACCESS.2024.3385787
- G. Holste, E.K. Oikonomou, B.J. Mortazavi, Z. Wang, R. Khera, Efficient Deep Learning-Based Automated Diagnosis from Echocardiography with Contrastive Self-Supervised Learning. Communications Medicine, 4(1), (2024) 133. https://doi.org/10.1038/s43856-024-00538-3
- A.D. Jamthikar, Q.A. Hathaway, K. Maganti, Y. Hamirani, S. Bokhari, N. Yanamala, P.P. Sengupta, Ultrasonic Texture Analysis for Predicting Acute Myocardial Infarction. JACC: Cardiovascular Imaging, 18(11), (2025) 1185–1199. https://doi.org/10.1016/j.jcmg.2025.06.018
- Y. Wang, Q. Zhou, J. Liu, J. Xiong, G. Gao, X. Wu, L.J. Latecki, (2019) LedNet: A Lightweight Encoder-Decoder Network for Real-Time Semantic Segmentation. In 2019 IEEE International Conference on Image Processing (ICIP), IEEE, Taipei, Taiwan. https://doi.org/10.1109/ICIP.2019.8803154
- M. Yang, K. Yu, C. Zhang, Z. Li, K. Yang, (2018). DenseASPP for Semantic Segmentation in Street Scenes. In 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, IEEE, Salt Lake City, UT, USA. https://doi.org/10.1109/CVPR.2018.00388
- R. Muraki, A. Teramoto, K. Sugimoto, K. Sugimoto, A. Yamada, E. Watanabe, Automated Detection Scheme for Acute Myocardial Infarction using Convolutional Neural Network and Long Short-Term Memory. PLOS ONE, 17(2), (2022) e0264002. https://doi.org/10.1371/journal.pone.0264002
- A. Degerli, HMC-QU echocardiography dataset, Kaggle Dataset, 2021. Available at: https://www.kaggle.com/datasets/aysendegerli/hmcqu-dataset (accessed 15 September 2026).
- M. Alessandrini, B. Chakraborty, B. Heyde, O. Bernard, M. De Craene, M. Sermesant, J. D’Hooge, Realistic Vendor-Specific Synthetic Ultrasound Data for Quality Assurance of 2-D Speckle Tracking Echocardiography: Simulation Pipeline and Open Access Database. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 65(3), (2017) 411–422. https://doi.org/10.1109/TUFFC.2017.2786300
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